Guideline Detail

Clinical Guidelines for the Management of HIV & AIDS in Adults and Adolescents

Source: South Africa National Department of Health
Publication Date: April 1, 2010

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2010 antiretroviral management guidelines from the South Africa National Department of Health. Topics addressed include standardised national eligibility criteria for starting antiretroviral therapy (ART) regimens for adults and adolescents; standardised national ART regimens for adults and adolescents; standardised national monitoring for adults and adolescents with HIV; standardised national ART regimens for HIV-positive pregnant women and their infants; visit scheduling for adults with HIV; first-line therapy for treatment-naive patients; clinical and laboratory monitoring of patients on first line treatment; adherence support, assessment, and monitoring; what to expect in the first 4 months of therapy; when to switch ART regimens; substituting drugs in the first-line regimen; treatment failure; clinical and laboratory monitoring of patients on second-line treatment; management of treatment failure after second-line treatment; management of patients previously treated with ART; treatment interruptions; patients with tuberculosis (TB); patients with hepatitis B virus; patients with anaemia; expectations regarding care; diagnosis and management of adverse events; key adverse events; routine patient management; TB screening, prevention, and diagnosis; isoniazid prophylaxis; clinical HIV stage; opportunistic infection diagnosis and management; CD4+ cell count and HIV-1 RNA monitoring; cotrimoxazole prophylaxis; sexually transmitted infection screening; Pap smear; immunizations; family planning; mental health screening; HIV transmission and reinfection prevention; support provision; and contraindications and special considerations.

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Keywords: HIV - Resource-Limited Settings, HIV - First-line Therapy, HIV - Monitoring, HIV - Adherence, HIV - Treatment-Experienced Patients, HIV - Tuberculosis, HIV - Adverse Events, HIV - Switch Strategies, HIV - Viral Hepatitis Coinfection, HIV - Pregnancy