South Africa National Department of Health
Publication Date: April 1, 2010
2010 antiretroviral management guidelines from the South Africa National Department of Health. Topics addressed include standardised national eligibility criteria for starting antiretroviral therapy (ART) regimens for adults and adolescents; standardised national ART regimens for adults and adolescents; standardised national monitoring for adults and adolescents with HIV; standardised national ART regimens for HIV-positive pregnant women and their infants; visit scheduling for adults with HIV; first-line therapy for treatment-naive patients; clinical and laboratory monitoring of patients on first line treatment; adherence support, assessment, and monitoring; what to expect in the first 4 months of therapy; when to switch ART regimens; substituting drugs in the first-line regimen; treatment failure; clinical and laboratory monitoring of patients on second-line treatment; management of treatment failure after second-line treatment; management of patients previously treated with ART; treatment interruptions; patients with tuberculosis (TB); patients with hepatitis B virus; patients with anaemia; expectations regarding care; diagnosis and management of adverse events; key adverse events; routine patient management; TB screening, prevention, and diagnosis; isoniazid prophylaxis; clinical HIV stage; opportunistic infection diagnosis and management; CD4+ cell count and HIV-1 RNA monitoring; cotrimoxazole prophylaxis; sexually transmitted infection screening; Pap smear; immunizations; family planning; mental health screening; HIV transmission and reinfection prevention; support provision; and contraindications and special considerations.
Keywords: HIV - Resource-Limited Settings, HIV - First-line Therapy, HIV - Monitoring, HIV - Adherence, HIV - Treatment-Experienced Patients, HIV - Tuberculosis, HIV - Adverse Events, HIV - Switch Strategies, HIV - Viral Hepatitis Coinfection, HIV - Pregnancy