Southern African Society for Paediatric Infectious Diseases
Publication Date: January 1, 2009
2009 guidelines from the Southern African Society for Paediatric Infectious Diseases designed to increase awareness of the burden of childhood tuberculosis (TB) in Southern Africa, to increase case finding, and to align management with more standard contemporary practice. Topics covered include: epidemiology; clinical presentation including hypersensitivity phenomena, constitutional symptoms, pulmonary disease, and extrapulmonary disease; diagnosis including symptom-based approach, tuberculin skin test, chest radiograph, microscopy and culture, interferon gamma release assays, and nucleic acid amplification tests; referral for specialist opinion; management of infection; personal protection; treatment including uncomplicated TB, complicated TB, TB meningitis, miliary TB, indications for the use of corticosteroids, retreatment cases, drug-related adverse events, paradoxical reactions, and advice to parents and caregivers; recording and reporting; special issues to consider including drug-resistant TB, and TB/HIV coinfection in children; and prevention including preventive therapy, Bacillus Calmette-Guérin immunisation, and babies born to TB-infected mothers.
Keywords: HIV - Tuberculosis, Tuberculosis - Adverse Events, Tuberculosis - Biomedical Prevention, Tuberculosis - Drug Resistance, Tuberculosis - Epidemiology, Tuberculosis - First-line Therapy, Tuberculosis - Paediatrics, Tuberculosis - Resource-Limited Settings, Tuberculosis - Tests and Assays, Tuberculosis - Transmission and Prevention