Guideline Detail

Interim WHO Clinical Staging of HIV/AIDS and HIV/AIDS Case Definitions for Surveillance: African Region

Source: World Health Organisation
Publication Date: June 16, 2005

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Interim guidance from the World Health Organisation based on an international drafting meeting held in Saas Fee in June 2004 and on recommendations made by experts from African countries at a meeting held in Nairobi in December 2004. The goals of the proposed revisions are to: provide greater consistency between adult and paediatric staging systems; harmonise clinical case definitions and surveillance definitions; provide clinical and immunologic staging for adults and children based on the degree of immunocompromise and prognosis, but that facilitates follow-up care; provide guidance on the care of children younger than 18 months of age; facilitate the use of the clinical staging system and HIV/AIDS case definitions by nonspecialist and nonpaediatric healthcare workers at the basic level and in peripheral healthcare facilities; assist with clinical decision making, including decisions on starting, substituting, switching, and stopping antiretroviral therapy and with routine follow-up of patients on treatment; permit the inclusion of laboratory testing, especially CD4+ cell count, where available, so as to guide prognosis and assist in determining the need for antiretroviral therapy and other therapies; and provide surveillance definitions for advanced stages of HIV infection that reflect disease requiring antiretroviral therapy either immediately or in the near future.

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Keywords: HIV - Acute HIV Infection, HIV - Cryptococcus, HIV - Cytomegalovirus (CMV), HIV - Diagnosis, HIV - Herpes Simplex Virus, HIV - Dermatologic Complications, HIV - Malignancies, HIV - Monitoring, HIV - Neurologic Complications, HIV - Neutropenia, HIV - Paediatric/Adolescent Patients, HIV - Pneumocystis jiroveci pneumonia (PCP), HIV - Resource-Limited Settings, HIV - Tuberculosis, HIV - Wasting