World Health Organisation
Publication Date: June 16, 2005
Interim guidance from the World Health Organisation based on an international drafting meeting held in Saas Fee in June 2004 and on recommendations made by experts from African countries at a meeting held in Nairobi in December 2004. The goals of the proposed revisions are to: provide greater consistency between adult and paediatric staging systems; harmonise clinical case definitions and surveillance definitions; provide clinical and immunologic staging for adults and children based on the degree of immunocompromise and prognosis, but that facilitates follow-up care; provide guidance on the care of children younger than 18 months of age; facilitate the use of the clinical staging system and HIV/AIDS case definitions by nonspecialist and nonpaediatric healthcare workers at the basic level and in peripheral healthcare facilities; assist with clinical decision making, including decisions on starting, substituting, switching, and stopping antiretroviral therapy and with routine follow-up of patients on treatment; permit the inclusion of laboratory testing, especially CD4+ cell count, where available, so as to guide prognosis and assist in determining the need for antiretroviral therapy and other therapies; and provide surveillance definitions for advanced stages of HIV infection that reflect disease requiring antiretroviral therapy either immediately or in the near future.
Keywords: HIV - Acute HIV Infection, HIV - Cryptococcus, HIV - Cytomegalovirus (CMV), HIV - Diagnosis, HIV - Herpes Simplex Virus, HIV - Dermatologic Complications, HIV - Malignancies, HIV - Monitoring, HIV - Neurologic Complications, HIV - Neutropenia, HIV - Paediatric/Adolescent Patients, HIV - Pneumocystis jiroveci pneumonia (PCP), HIV - Resource-Limited Settings, HIV - Tuberculosis, HIV - Wasting