Guideline Detail

The 2012 Southern African ARV Drug Resistance Testing Guidelines

Source: Southern African HIV Clinicians Society
Publication Date: November 1, 2012

View Guideline

2012 resistance testing recommendations from the Southern African HIV Clinicians Society. Topics addressed include recommendations for antiretroviral (ARV) drug resistance testing, including in the diagnosis of HIV in children younger than 2 years of age, failure of ARV regimens, and acute infection; scenarios where ARV resistance testing is not recommended, including HIV diagnosis in adults and adolescents, ARV initiation in adults and children older than 2 years of age, and treatment interruptions without documented regimen failure; national integration of public sector laboratories; surveillance of ARV drug resistance; monitoring and evaluation; causes of and interventions for nonadherence, including inadequate treatment literacy, adverse effects, depression and mental illness, poverty and food insecurity, work-related issues, substance use, social problems, denial, pill burden, altered fertility intentions, and conflict of opinions; laboratory objectives; practical issues for genotypic ARV resistance testing; genotypic ARV resistance assays; and research priorities, including resistance assays and operational research activities.

Browse All Guidelines

Keywords: HIV - Resistance Testing, HIV - Treatment-Experienced Patients, HIV - Resource-Limited Settings