South African Society for Paediatric Infectious Diseases
Publication Date: January 1, 2009
2009 recommendations on the diagnosis and treatment of tuberculosis (TB) in children. Topics addressed include: epidemiology; clinical presentation, including hypersensitivity phenomena, constitutional symptoms, pulmonary disease, and extrapulmonary disease; diagnosis via the symptom-based approach, tuberculin skin test, chest radiograph, microscopy and culture, interferon-gamma release assays, and nucleic acid amplification tests; referral for specialist opinion; inpatient and outpatient infection control; personal protection; treatment of uncomplicated TB, complicated TB, TB meningitis, and military TB; indications for the use of corticosteroids; retreatment cases; drug-related adverse events; paradoxical reaction; advice to parents/caregivers; recording and reporting; special issues, including drug-resistant TB, and TB/HIV coinfection; preventive therapy; immunisation; and infants born to mothers with TB.
Keywords: Tuberculosis - Resource-Limited Settings, HIV - Tuberculosis, Tuberculosis - Adverse Events, Tuberculosis - Biomedical Prevention, Tuberculosis - Drug Resistance, Tuberculosis - Epidemiology, Tuberculosis - First-line Therapy, Tuberculosis - Paediatrics, Tuberculosis - Tests and Assays, Tuberculosis - Transmission and Prevention, Tuberculosis - Treatment Complications, Tuberculosis - Adherence, Tuberculosis - Salvage Therapy, Tuberculosis - Neurologic Complications, Tuberculosis - IRIS