World Health Organisation
Publication Date: May 1, 2016
2016 World Health Organisation recommendations for managing drug-resistant tuberculosis. This update is intended as a tool for use by health professionals in response to the 62nd World Health Assembly’s call for Member States to develop a comprehensive framework for the management and care of multidrug-resistant (MDR) tuberculosis (TB) and extensively drug-resistant TB. Topics addressed include rapid drug susceptibility testing for early start of appropriate treatment; monitoring the response to MDR TB treatment; composition and duration of second-line anti-TB regimens; use of antiretrovirals in patients on second-line anti-TB regimens; models of care for managing MDR TB; and potentially overlapping toxicities of antiretrovirals and anti-TB agents.